ESRS评分联合BPV对aSAH介入栓塞术后DCI的警示作用
成 刚 岳 勇 黄海林 王晓毅 张 烨
电子科技大学医学院附属绵阳医院·绵阳市中心医院,四川 绵阳 621000
通信作者:张烨
【摘要】 目的 探讨 ESSEN 卒中风险评分联合血压变异性指数(BPV)对颅内动脉瘤性蛛网膜下腔出血(aSAH)介入栓塞术后迟发性脑缺血(DCI)的警示作用。方法 选择 2019-01—2021-12 绵阳市中心医院收治的 129 例拟行介入栓塞术治疗的 aSAH 患者,根据术后是否发生 DCI 分为 DCI 组(39 例)和非 DCI 组(90 例)。所有患者术前评估 ESRS 评分,测量 BPV,收集临床相关信息,分析影响 aSAH 后 DCI 的相关因素以及 ESRS 评分、BPV 预测 aSAH 后 DCI 的效能。结果 DCI 组年龄、入院时收缩压、Hunt-Hess 分级Ⅲ~Ⅴ级、改良 Fisher 分级Ⅲ~Ⅴ级比例,ESRS 评分(4.02±1.15 分 vs 2.42±0.71 分 )和 BPV(21.53±6.09 vs 16.02±4.15)高于非 DCI 组(P<0.05)。Hunt-Hess 分级Ⅲ~Ⅴ级(OR=3.438,95% CI:1.728~6.841)、ESRS 评分(OR=2.284,95% CI:1.499~3.481)、BPV(OR=1.826,95% CI:1.261~2.644)是 aSAH 后是否发生 DCI 的危险因素(P<0.05)。ESRS 评分、BPV 单独预测 aSAH 后 DCI 的曲线下面积为 0.655、0.734,联合两项预测 aSAH后 DCI 的曲线下面积为 0.878,高于单独 ESRS 评分、BPV 单独预测(Z=4.319、3.185,P<0.05)。结论 高ESRS 评分和 BPV 与 aSAH 后发生 DCI 有关,联合 ESRS 评分和 BPV 可有效地预测 aSAH 后 DCI 的发生。
【关键词】 颅内动脉瘤;蛛网膜下腔出血;血压变异;ESSEN 卒中风险评分
【中图分类号】 R739.41 【文献标识码】 A 【文章编号】 1673-5110 (2022) 05-0565-05
基金项目:四川省卫生和计划生育委员会科研项目(编号:21PJ178)
DOI:10.12083/SYSJ.220381
The warning effect of ESRS score combined with BPV on DCI after interventional embolization of intracranial in aSAH patients
CHENG Gang,YUE Yong,HUANG Hailin,WANG Xiaoyi,ZHANG Ye
Mianyang Hospital Affiliated to School of Medicine,University of Electronic Science and Technology of China·Mianyang Central Hospital,Mianyang 621000,China
Corresponding author: ZHANG Ye
【Abstract】 Objective To investigate the warning effect of ESSEN stroke risk score combined with blood pressure variability index on delayed cerebral ischemia (DCI) after interventional embolization of aneurysmal subarachnoid hemorrhage(aSAH). Methods 129 aSAH patients who were admitted to our hospital from January 2019 to December 2021 were selected and divided into DCI group(39 cases)and non-DCI group(90 cases) according to postoperatively DCI. All patients were evaluated for ESRS score,BPV before surgery was measured,and clinical information was collected to analyze the related factors affecting DCI after aSAH and the efficacy of ESRS score and BPV in predicting DCI after aSAH. Results Age,systolic blood pressure at admission,hunt-Hess grade ⅲ to ⅴ,modified Fisher grade Ⅲ to Ⅴ,ESRS score(4.02±1.15 scores vs 2.42±0.71 scores) and BPV (21.53 ± 6.09 vs 16.02 ± 4.15) of DCI group were higher than those of non-DCI group (P<0.05). Hunt-Hess grade Ⅲ to Ⅴ(OR=3.438,95% CI:1.728~6.841),ESRS score(OR=2.284,95% CI:1.499~3.481)and BPV(OR=1.826,95% CI:1.261~2.644)were the risk factors for DCI after aSAH(P<0.05). The area under curve of ESRS score and BPV alone diagnosing DCI after aSAH were 0.655 and 0.734,and the area under curve of combined ESRS score and BPV was 0.878,which was higher than that predicted by ESRS score and BPV alone(Z=4.319,3.185,P<0.05). Conclusion High ESRS score and BPV are associated with DCI after aSAH,and combined ESRS score and BPV can effectively predict the occurrence of DCI after aSAH.
【Key words】 Intracranial aneurysm;Subarachnoid hemorrhage;Blood pressure variation;ESSEN Stroke risk Score