Construction and application of home nursing scheme for patients with Alzheimer’s disease ZHOU Na Zhengzhou Ninth People’s Hospital,Zhengzhou 450000,China Corresponding author:ZHOU Na 【Abstract】 Objective To formulate a home care plan for patients with Alzheimer’s disease(AD)after discharge and explore its application effect. Methods Patients with AD in our hospital from February 2019 to May 2020 were randomly divided into observation group and control group. The control group received routine nursing guidance,while the observation group received home nursing plan. The activities of daily living,RTC (refusal to cooperate),mental and behavioral symptoms,caregiver burden,and the use of antipsychotic drugs were compared and analyzed between the two groups within 12 months after discharge. Results (1)The RTC and average daily activity time of patients in the two groups changed significantly at 6 or 12 months after discharge (P<0.017). However,between the two groups,the RTC score of the observation group was significantly lower than that of the control group at 12 months after discharge(the refusal to cooperate changed for the better),and the difference was significant(P<0.05). There was no significant difference in ADL after discharge(P>0.05).(2) The scores of caregivers’burden and mental and behavioral symptoms in the observation group were significantly lower than those in the control group 12 months after discharge(caregivers’ burden and mental and behavioral symptoms changed for the better).(3)The application of antipsychotic drugs in the two groups was similar after discharge,and there was no significant difference(P>0.05). However,the usage rate of various drugs in the observation group was lower than that in the control group,especially at 12 months after discharge. Conclusion Home-based nursing program can improve the resistance to nursing behavior and mental behavior symptoms of AD patients,and relieve the care burden of family members,but it cannot improve the daily living ability of patients. 【Key words】Alzheimer’s disease;Home care;Construction;Psychobehavioral symptoms