脑白质病变危险因素及发病机制的研究进展
任腊梅 郭爱红 高春燕 丁江博 王丙聚
延安大学咸阳医院，陕西 咸阳 712000
通信作者：王丙聚
【摘要】 随着影像学技术的发展，脑白质病变的高检出率越来越引起人们的重视。但目前关于脑白质病变的危险因素和发病机制还存在许多问号，在脑白质病变的众多可能危险因素中只有年龄和高血压被予以了肯定，而其余的危险因素尚无明确结论。而对于脑白质病变的发病机制也缺乏有说服力的共识。本文就脑白质病变的危险因素和发病机制方面进行综述，为脑白质病变的防治提供一定的思路。
【关键词】 脑白质病变；脑小血管病变；危险因素；发病机制；脑缺血
【中图分类号】 R741 【文献标识码】 A 【文章编号】 1673-5110 （2022） 07-0916-04
基金项目：陕西省重点研发计划（编号：2020SF-150）
DOI：10.12083/SYSJ.220547
Research progress on risk factors and pathogenesis of white matter lesions
REN Lamei，GUO Aihong，GAO Chunyan，DING Jiangbo，WANG Bingju
Yan’an University Xianyang Hospital，Xianyang 712000，China
Corresponding author：WANG Bingju
【Abstract】 With the development of imaging technology，more and more attention has been paid to the high detection rate of white matter lesions. However，there are still many question marks about the risk factors and pathogenesis of white matter lesions. Of the many possible risk factors for white matter lesions，only age and hypertension have been identified，while the rest have not been conclusively identified. There is also a lack of convincing consensus on the pathogenesis of white matter lesions. This article reviews the risk factors and pathogenesis of white matter lesions，and provides some ideas for the prevention and treatment of white matter lesions.
【Key words】White matter lesions；Cerebral vascular disease；Risk factors；Pathogenesis；Cerebral ischemia
